Twitter Inc may cut 8 percent of its workforce or about 300 people, Bloomberg reported on Monday.
The job cuts could be announced before the company reports third-quarter earnings on Thursday.
Twitter has refused to comment on the matter.
Last year, Twitter announced plans to lay off up to 336 employees, or about 8 percent of its workforce.
The company had 3,860 employees globally as of June.
Twitter was one of a number of major websites, including Spotify and Reddit, that were affected on Friday by a large cyber attack.
The company confirmed in September it would lay off some employees and halt engineering work at one of its development centers.
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