A new study by the Cleveland Clinic has found that individuals who have previously been infected with COVID-19 receive no additional benefits from vaccination.
The study was conducted on 52,238 employees in the Cleveland Clinic. A positive RT-PCR test was considered to define COVID-19 infection. The participants received two doses of the Pfizer/BioNTech or Moderna COVID-19 vaccine at an interval of 28 days. A participant who tested positive for COVID-19 at least 42 days before the vaccination initiation was considered previously infected.
During the course of the study, infection occurred almost exclusively in participants who were not previously infected and were not vaccinated.
No significant difference in COVID-19 incidence was observed between previously infected and currently vaccinated participants.
Not a single incidence of COVID-19 infection was observed in previously infected participants with or without vaccination.
Based on the study findings, COVID-19 vaccination should be prioritized for individuals who have not had prior COVID-19 infection.
A ZOE COVID Symptom Study recently found that individuals with previous COVID-19 infection were 2x more likely to experience adverse reactions post-vaccination. Another recent study also found that individuals with prior COVID-19 infection more frequently reported side effects.